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Fibromyalgia syndrome (FMS) is a mysterious rheumatic disease. Affected persons complain about diffuse chronic muscle pain near the joint (but not in the joint itself) and about exhaustion, sleep disorders, depression and a myriad of other complaints. There are no symptoms that clearly indicate the disease. Therefore, fibromyalgia is often diagnosed with the help of a complex exclusion procedure. It can take 5-10 years from the time of the first symptoms to a definitive diagnosis – a period of time that is often painful for sufferers and marked by uncertainty (https://www.rheumaliga.ch/rheuma-von-a-z/fibromyalgie).
There are no figures on the frequency of fibromyalgia. Estimates assume about 0.5% to 5% of the population. In Switzerland one speaks therefore of 40’000 to 400’000 affected persons.
Fibromyalgia is still considered incurable. For this reason, scientists and researchers have been working flat out for some time to find an effective antidote. In the course of this research, the first studies have been published in recent years, which have examined the treatment of fibromyalgia with cannabinoids such as cannabidiol (CBD) and medical cannabis in more detail.
Fibromyalgia in science
To date, detailed scientific studies on the effectiveness of CBD in alleviating symptoms of fibromyalgia are still lacking. In the following, cbuy.ch therefore presents the few promising scientific approaches:
Endocannabinoids: Initial findings suggest that endocannabinoids may have a beneficial effect on the anti-inflammatory process in fibromyalgia patients, as they consist of lipid precursors. Lipids are natural substances occurring in living organisms, which are mainly used as structural components in cell membranes, as energy stores or as signal molecules. These then release cannabinoid receptors with the help of neurotransmitters or immune cells, so that they can activate neighbouring cells and exert their anti-inflammatory effect.
Lipo-amino acids: lipo-amino acids, an endogenous subfamily of the eicosanoids, are structurally and metabolically related to the endocannabinoids and have similar anti-inflammatory and analgesic properties. However, their efficacy in relation to fibromyalgic symptoms has yet to be thoroughly investigated scientifically.
In summary, research into the treatment of fibromyalgia with cannabinoids is making progress and has already produced some initial findings. Endocannabinoids and lipo-amino acids seem to be particularly promising for further investigations. Both have anti-inflammatory and analgesic characteristics due to their structural make-up – properties that play a central role in the treatment of fibromyalgia.